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mutant ythdc1  (Addgene inc)


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    Addgene inc mutant ythdc1
    Fig. 2. <t>YTHDC1</t> Knockdown Prolongs the Duration of the Early Stage of Mitosis
    Mutant Ythdc1, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mutant ythdc1/product/Addgene inc
    Average 93 stars, based on 7 article reviews
    mutant ythdc1 - by Bioz Stars, 2026-03
    93/100 stars

    Images

    1) Product Images from "N 6 -Methyladenosine Reader Protein YTHDC1 Supports Proper Mitotic Progression Partly through Regulation of TPX2-Aurora A Signaling."

    Article Title: N 6 -Methyladenosine Reader Protein YTHDC1 Supports Proper Mitotic Progression Partly through Regulation of TPX2-Aurora A Signaling.

    Journal: Biological & pharmaceutical bulletin

    doi: 10.1248/bpb.b24-00542

    Fig. 2. YTHDC1 Knockdown Prolongs the Duration of the Early Stage of Mitosis
    Figure Legend Snippet: Fig. 2. YTHDC1 Knockdown Prolongs the Duration of the Early Stage of Mitosis

    Techniques Used: Knockdown

    Fig. 3. The Spindle Assembly Checkpoint Is Involved in the YTHDC1 Knockdown-Induced Delay in Mitotic Progression
    Figure Legend Snippet: Fig. 3. The Spindle Assembly Checkpoint Is Involved in the YTHDC1 Knockdown-Induced Delay in Mitotic Progression

    Techniques Used: Knockdown

    Fig. 4. YTHDC1 Supports Mitotic Progression Partly through Regulation of Centrosomal Abundance of Aurora A
    Figure Legend Snippet: Fig. 4. YTHDC1 Supports Mitotic Progression Partly through Regulation of Centrosomal Abundance of Aurora A

    Techniques Used:

    Fig. 5. YTHDC1 Represses the Centrosomal Abundance of Aurora A through the Regulation of TPX2 Expression
    Figure Legend Snippet: Fig. 5. YTHDC1 Represses the Centrosomal Abundance of Aurora A through the Regulation of TPX2 Expression

    Techniques Used: Expressing



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    mutant ythdc1  (Addgene inc)
    93
    Addgene inc mutant ythdc1
    Fig. 2. <t>YTHDC1</t> Knockdown Prolongs the Duration of the Early Stage of Mitosis
    Mutant Ythdc1, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mutant ythdc1/product/Addgene inc
    Average 93 stars, based on 1 article reviews
    mutant ythdc1 - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Fig. 2. YTHDC1 Knockdown Prolongs the Duration of the Early Stage of Mitosis

    Journal: Biological & pharmaceutical bulletin

    Article Title: N 6 -Methyladenosine Reader Protein YTHDC1 Supports Proper Mitotic Progression Partly through Regulation of TPX2-Aurora A Signaling.

    doi: 10.1248/bpb.b24-00542

    Figure Lengend Snippet: Fig. 2. YTHDC1 Knockdown Prolongs the Duration of the Early Stage of Mitosis

    Article Snippet: Doxycycline (Dox)-inducible cell lines expressing FLAG and HA-tagged wild-type or mutant YTHDC1 (A549/YTHDC1-WT or -W377A/W428A) were established as previously described.11) Plasmids pcDNA3-FLAG-HA-hYTHDC1 was a gift from Samie Jaffrey (Addgene plasmid # 85167; http://n2t.net/ addgene:85167; RRID:Addgene_85167).12) FLAG-HA epitopetagged YTHDC1 was subcloned into pENTR4-no-ccDB (686-1) [a gift from Eric Campeau & Paul Kaufman (Addgene plasmid # 17424; http://n2t.net/addgene:17424; RRID: Addgene_17424)].13) The small interfering RNA (siRNA)-resistant YTHDC1 plasmid was created by introducing a silent mutation into the siYTHDC1#1 target site by PCR using the following primers: (sense) 5′-CTGGTCTCCAAGCCACTGAGCTCATCTGTTAGC-3′ and (antisense) 5′-CTGCCTCGAATGGACAGAAGGCTTTTGTCG-3′.

    Techniques: Knockdown

    Fig. 3. The Spindle Assembly Checkpoint Is Involved in the YTHDC1 Knockdown-Induced Delay in Mitotic Progression

    Journal: Biological & pharmaceutical bulletin

    Article Title: N 6 -Methyladenosine Reader Protein YTHDC1 Supports Proper Mitotic Progression Partly through Regulation of TPX2-Aurora A Signaling.

    doi: 10.1248/bpb.b24-00542

    Figure Lengend Snippet: Fig. 3. The Spindle Assembly Checkpoint Is Involved in the YTHDC1 Knockdown-Induced Delay in Mitotic Progression

    Article Snippet: Doxycycline (Dox)-inducible cell lines expressing FLAG and HA-tagged wild-type or mutant YTHDC1 (A549/YTHDC1-WT or -W377A/W428A) were established as previously described.11) Plasmids pcDNA3-FLAG-HA-hYTHDC1 was a gift from Samie Jaffrey (Addgene plasmid # 85167; http://n2t.net/ addgene:85167; RRID:Addgene_85167).12) FLAG-HA epitopetagged YTHDC1 was subcloned into pENTR4-no-ccDB (686-1) [a gift from Eric Campeau & Paul Kaufman (Addgene plasmid # 17424; http://n2t.net/addgene:17424; RRID: Addgene_17424)].13) The small interfering RNA (siRNA)-resistant YTHDC1 plasmid was created by introducing a silent mutation into the siYTHDC1#1 target site by PCR using the following primers: (sense) 5′-CTGGTCTCCAAGCCACTGAGCTCATCTGTTAGC-3′ and (antisense) 5′-CTGCCTCGAATGGACAGAAGGCTTTTGTCG-3′.

    Techniques: Knockdown

    Fig. 4. YTHDC1 Supports Mitotic Progression Partly through Regulation of Centrosomal Abundance of Aurora A

    Journal: Biological & pharmaceutical bulletin

    Article Title: N 6 -Methyladenosine Reader Protein YTHDC1 Supports Proper Mitotic Progression Partly through Regulation of TPX2-Aurora A Signaling.

    doi: 10.1248/bpb.b24-00542

    Figure Lengend Snippet: Fig. 4. YTHDC1 Supports Mitotic Progression Partly through Regulation of Centrosomal Abundance of Aurora A

    Article Snippet: Doxycycline (Dox)-inducible cell lines expressing FLAG and HA-tagged wild-type or mutant YTHDC1 (A549/YTHDC1-WT or -W377A/W428A) were established as previously described.11) Plasmids pcDNA3-FLAG-HA-hYTHDC1 was a gift from Samie Jaffrey (Addgene plasmid # 85167; http://n2t.net/ addgene:85167; RRID:Addgene_85167).12) FLAG-HA epitopetagged YTHDC1 was subcloned into pENTR4-no-ccDB (686-1) [a gift from Eric Campeau & Paul Kaufman (Addgene plasmid # 17424; http://n2t.net/addgene:17424; RRID: Addgene_17424)].13) The small interfering RNA (siRNA)-resistant YTHDC1 plasmid was created by introducing a silent mutation into the siYTHDC1#1 target site by PCR using the following primers: (sense) 5′-CTGGTCTCCAAGCCACTGAGCTCATCTGTTAGC-3′ and (antisense) 5′-CTGCCTCGAATGGACAGAAGGCTTTTGTCG-3′.

    Techniques:

    Fig. 5. YTHDC1 Represses the Centrosomal Abundance of Aurora A through the Regulation of TPX2 Expression

    Journal: Biological & pharmaceutical bulletin

    Article Title: N 6 -Methyladenosine Reader Protein YTHDC1 Supports Proper Mitotic Progression Partly through Regulation of TPX2-Aurora A Signaling.

    doi: 10.1248/bpb.b24-00542

    Figure Lengend Snippet: Fig. 5. YTHDC1 Represses the Centrosomal Abundance of Aurora A through the Regulation of TPX2 Expression

    Article Snippet: Doxycycline (Dox)-inducible cell lines expressing FLAG and HA-tagged wild-type or mutant YTHDC1 (A549/YTHDC1-WT or -W377A/W428A) were established as previously described.11) Plasmids pcDNA3-FLAG-HA-hYTHDC1 was a gift from Samie Jaffrey (Addgene plasmid # 85167; http://n2t.net/ addgene:85167; RRID:Addgene_85167).12) FLAG-HA epitopetagged YTHDC1 was subcloned into pENTR4-no-ccDB (686-1) [a gift from Eric Campeau & Paul Kaufman (Addgene plasmid # 17424; http://n2t.net/addgene:17424; RRID: Addgene_17424)].13) The small interfering RNA (siRNA)-resistant YTHDC1 plasmid was created by introducing a silent mutation into the siYTHDC1#1 target site by PCR using the following primers: (sense) 5′-CTGGTCTCCAAGCCACTGAGCTCATCTGTTAGC-3′ and (antisense) 5′-CTGCCTCGAATGGACAGAAGGCTTTTGTCG-3′.

    Techniques: Expressing